Cure-Coming Trained By JP - 60 servings
- Ultra-absorbable curcumin
- Ultra-potent patented BCM-95® Curcumin
- Antioxidant and anti-inflammatory properties
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TrainedbyJP Nutrition Cure-Coming
TrainedbyJP Nutrition brings to you Cure-Coming, an ultra-absorbable curcumin for whole-body health support containing ultra-potent patented BCM-95® Curcumin which has been shown to aid in lowering systemic inflammation, brain/immune/digestive health as well as antioxidant support.
Curcumin, the bioactive component of turmeric, Curcuma longa has an exceptionally wide spectrum of activities most notably its antioxidant and anti-inflammatory properties. Most recently, it has also been postulated to have anti-depressive properties in major depressive patients as well as positive cognitive outcomes in older populations.
Curcumin inhibits pro-inflammatory transcription factors such as nuclear factor-kappa beta (NFK- B) which can effect joint inflammation. It also activates peroxisome proliferator–activated receptor gamma (PPAR-γ) and Nrf2 cell signaling pathways, leading to the downregulation of tumor necrosis factor (TNF) and interleukin-6 (IL-6), and upregulates adiponectin (the hormone involved in blood glucose and fatty acid breakdown made by adipose fat tissue).
In simple terms, curcumin has the potential to lower C-Reactive Protein (CRP; a measure of inflammation in the body), induce autophagy through mTOR inhibition (the selective destruction of damaged cellular organelles), protect against cardiac hypertrophy, and potentially decrease artherosclerosis risk.
Despite the promising nutritional and pharmacological properties of curcumin, it exhibits low aqueous solubility, poor gastrointestinal absorption and poor bioavailability.
Its high rate of metabolism, metabolic inactivation and rapid elimination from the body makes it difficult to yield appreciable plasma concentrations. Because of its poor oral absorption, it is difficult for orally administered curcumin to reach blood levels sufficient to exert its bioactivities. Poor absorption from the gut and avid metabolism in the body is cited as reasons for the lack of systemic availability.
To overcome this problem, several curcumin preparations with drug-delivery systems (DDS) have been developed to increase the bioavailability of curcumin after oral administration.
Combinations with piperine have been most common. Piperine, an inhibitor of phase II liver metabolism and intestinal glucuronidation. In rats, the bioavailability of curcumin increased by 154% with piperine compared with a control group without piperine. In humans, piperine (20 mg/kg) was co-administered with curcumin (2 g) and the bioavailability was 20-times that of the control group. However, enhancing bioavailability by inhibiting phase II metabolism must be carefully carried out since many compounds are detoxified through this liver route which may be slowed by adminstering piperine.
BCM-95® is a novel bio-enhanced preparation of curcumin with the addition of phosphatidylcholine and turmeric essential oils (most notably aromatic tumerone volatile oil), which leads to enhanced and sustained absorption. In a human study, 2 g administration showed the bioavailability of BCM-95 (based on curcumin Area Under Curve (AUC)) to be almost 6.93-fold higher than that of a control curcumin formulation with no additive. The half life was shown to be approx. 4.96 h compared to 2.6 h for the control. 2 g/day dose levels are well tolerated without even mild adverse reactions. However, the mechanisms of these enhancements are unknown.
TrainedbyJP Nutrition stands by this long standing patented form of BCM-95® curcumin and they are proud to produce Cure-Coming; a supplement which they believe supports the health of nearly every organ in your body.
FREE SHIPPING on orders over €60 (Ireland & Northern Ireland only).
We aim to despatch all orders within 1-2 working days.
All Ireland and Northern Ireland deliveries up to 30kg are sent on a next working day service with DPD, which in most cases arrive within 1-3 working days.
DPD deliver all our parcels Monday to Friday in a time slot between 8am - 6pm.
There are always two attempts of delivery of every parcel and after that the parcel will be sent back to our warehouse so make sure someone is at home on the day of delivery to avoid disappointment.
If a delivery is attempted at your address but no one is there to collect and sign your parcel a card should be put through your letter box. Leaflet will tell you how to contact the courier to arrange re-delivery.
If you do not hear from a courier after 4-8 days, please contact us by email at firstname.lastname@example.org.
We deliver to selected list of counties. For details please see the list below.
All delivery prices are provided for packages in weight up to 31kg.
|Country||Orders under €60||Orders over €60||Transit Time|
|Republic of Ireland||€5.99||FREE||1 to 3 days|
|Northern Ireland||€5.99||FREE||2 to 4 days|
|United Kingdom||€9.99||€9.99||3 to 5 days|
|France, Germany, Netherlands, Belgium, Luxembourg||€15.48||€15.48||3 to 5 days|
|Austria, Czech Republic, Denmark, Poland||€20.64||€20.64||4 to 7 days|
|Lithuania, Hungary, Slovakia, Slovenia||€24.51||€24.51||5 to 7 days|
|Sweden, Spain, Italy, Latvia, Estonia||€30.96||€30.96||5 to 8 days|
|Finland, Portugal||€34.83||€34.83||5 to 8 days|
For delivery to countries not listed, please contact us for information by email at email@example.com.
We want our customers to be happy with the goods they buy and about the service we provide. However if you are not happy with our products, we will take back any of our products and refund you in full. No question asked!
1. CANCELLATION POLICY / RIGHT TO CANCEL
1.1. You may cancel your contractual declaration in writing (e.g. letter or e-mail) within 14 days without justification, 14 days period begins on the day on which the customer acquires physical possession of the goods. 30% restocking charge will be applied.
1.2. The withdrawal period begins on the day on which the consumer acquires physical possession of the goods.
1.3. Timely sending of the cancellation or the item will suffice in protecting the cancellation period.
1.4. The costs of return any goods are paid by the customer.
PLEASE SUBMIT YOUR CANCELLATION TO:
Unit 5, Demesne Shopping Centre
Dundalk, Co. Louth
Republic of Ireland
2.1. We are always happy to accept any of our products.
2.2. To receive a full refund goods should be returned in original, unopened packaging.
2.3. If the product is not returned in its dispatched state we cannot offer a full refund and a compensation will be calculated on individual basis, please note that it can be up to 100% of value depending on the damage.
2.4. If goods have been dispatched, you have the right to return goods within 14 days of receipt of your goods.
2.5. In the event that you exercise your statutory right of revocation, you shall be responsible for regular costs of the return shipment if the goods supplied correspond to the goods ordered.
For further details on our Returns Policy, please contact us by email at firstname.lastname@example.org.